Deaths from COVID ‘incredibly rare’ among children

Nature.com Studies find that overall risk of death or severe disease from COVID-19 is very low in kids. July 15, 2021 Heidi Ledford A comprehensive analysis of hospital admissions and reported deaths across England suggests that COVID-19 carries a lower risk of dying or requiring intensive care among children and young people than was previously…

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SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans

Published: 24 May 2021   Abstract Long-lived bone marrow plasma cells (BMPCs) are a persistent and essential source of protective antibodies1,2,3,4,5,6,7. Individuals who have recovered from COVID-19 have a substantially lower risk of reinfection with SARS-CoV-28,9,10. Nonetheless, it has been reported that levels of anti-SARS-CoV-2 serum antibodies decrease rapidly in the first few months after…

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Had COVID? You’ll probably make antibodies for a lifetime

26 May 2021 Correction 27 May 2021 People who recover from mild COVID-19 have bone-marrow cells that can churn out antibodies for decades, although viral variants could dampen some of the protection they offer. Many people who have been infected with SARS-CoV-2 will probably make antibodies against the virus for most of their lives. So…

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Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

Wen Shi Lee, Adam K. Wheatley, Stephen J. Kent & Brandon J. DeKosky Nature Microbiology Abstract Antibody-based drugs and vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being expedited through preclinical and clinical development. Data from the study of SARS-CoV and other respiratory viruses suggest that anti-SARS-CoV-2 antibodies could exacerbate COVID-19 through antibody-dependent enhancement…

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